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H4C14 (NM_003548) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H32049E1

  • Amount:

    50 ug

  • Cite ID#:

    EN5427357

  • Price:

    553$

  • Type:

    Recombinant Proteins

  • Research Field:

    Systemic lupus erythematosus

  • Product Description:

    Purified recombinant protein of Human histone cluster 2, H4a (HIST2H4A), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

  • Protein length:

    A DNA sequence encoding human full-length HIST2H4A

  • Expression Host:

    E. coli

  • Species:

    Human

  • Molecular Weight:

    11.2 kDa

  • Gene symbol:

    H4C14

  • Gene ID:

    8370

  • mRNA Refseq:

    NM_003548

  • Protein Refseq:

    NP_003539

  • Swiss-Prot No.:

    P62805, B2R4R0

  • Chromosome location:

    1q21.2

  • Pathway:

    Systemic lupus erythematosus

  • Summary:

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl

  • Synonyms:

    FO108; H4; H4-16; H4/n; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C15; H4F2; H4FN; HIST2H4; HIST2H4A

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  • Amount:50 ug
  • Price:553.00$

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