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FASTK (NM_006712) Human Recombinant Protein
Datasheet   

  • Catalog Number:

    E45H30346E1

  • Amount:

    50 ug

  • Cite ID#:

    EN5425658

  • Price:

    528$

  • Type:

    Recombinant Proteins

  • Product Description:

    Purified recombinant protein of Human Fas-activated serine/threonine kinase (FASTK), transcript variant 1, Leu200-Gln535, with N-terminal His tag, expressed in E. coli, 50ug

  • Protein length:

    A DNA sequence encoding the region(Leu200-Gln535) of FASTK

  • Expression Host:

    E. coli

  • Species:

    Human

  • Molecular Weight:

    38.2 kDa

  • Gene symbol:

    FASTK

  • Gene ID:

    10922

  • mRNA Refseq:

    NM_006712

  • Protein Refseq:

    NP_006703

  • Swiss-Prot No.:

    Q14296, A0A090N8Z7

  • Chromosome location:

    7q36.1

  • Function:

    Druggable Genome, Protein Kinase

  • Summary:

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]

  • Form:

    Liquid

  • Concentration:

    >50 ug/mL as determined by microplate BCA method

  • Purity:

    > 80% as determined by SDS-PAGE and Coomassie blue staining

  • Storage/Stability:

    Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

  • Storage Buffer:

    50mM Tris, 8M Urea, pH8.0.

  • Synonyms:

    FAST

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  • Amount:50 ug
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