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GALR1 Rabbit Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E28PT1844

  • Amount:

    100ul

  • Price:

    255$

  • Altername:

    GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1

  • Gene Name:

    GALR1

  • Protein Name:

    Galanin receptor type 1

  • Applications:

    IF,ELISA

  • Reactivity:

    Human,Mouse

  • Concentration:

    1 mg/ml

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

  • Human Gene Id:

    2587

  • Swiss-Prot No.:

    P47211

  • Mouse Gene Id:

    14427

  • Mouse Swiss Prot No:

    P56479

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210

  • Specificity:

    GALR1 Polyclonal Antibody detects endogenous levels of GALR1 protein.

  • Recommended Dilutions:

    IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

  • Molecular Weight:

    39kD

  • Form of Antibody:

    Liquid

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Source:

    Polyclonal, Rabbit,IgG

  • Background:

    The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],

  • Tissue Expression:

    Brain,Melanoma,Small intestine,

  • Cellular localization:

    Cell membrane; Multi-pass membrane protein.

  • Signaling Pathway:

    Neuroactive ligand-receptor interaction;

  • Function:

    function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunofluorescence analysis of LOVO cells, using GALR1 Antibody. The picture on the right is blocked with the synthesized peptide.

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  • Amount:100ul
  • Price:255.00$

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