Catalog Number:
E28PE4051Amount:
100ulPrice:
255$Gene Name:
PNPOApplications:
FCM,IHC,WBReactivity:
Human,Mouse,RatFormulation:
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.Immunogen:
Full length human recombinant protein of human PNPO(NP_060599) produced in HEK293T cell.Recommended Dilutions:
WB 1:4000, IHC 1:150, FCM 1:100Predicted Molecular Weight:
29.8kDaForm of Antibody:
LiquidStorage/Stability:
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.Source:
MouseIsotype:
IgG2aBackground:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.Purification:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)Uniprot ID:
Q9NVS9Gene ID:
NM_018129Clonality:
Monoclonal