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JNK1 (JNK1) (15H10) Mouse Monoclonal antibody
Datasheet   

  • Catalog Number:

    E28PE1667

  • Amount:

    100ul

  • Price:

    255$

  • Gene Name:

    MAPK8

  • Applications:

    WB

  • Reactivity:

    Human,Mouse,Rat

  • Formulation:

    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

  • Immunogen:

    Recombinant protein expressed in E.coli corresponding to amino acids 1-384 of human JNK1

  • Recommended Dilutions:

    WB 1:1000

  • Predicted Molecular Weight:

    44kDa

  • Form of Antibody:

    Liquid

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Source:

    Mouse

  • Isotype:

    IgG2a

  • Background:

    JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK1 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of JNK1 by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. JNK1 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of JNK1 gene suggested that it play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported

  • Purification:

    Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

  • Uniprot ID:

    P45983

  • Gene ID:

    NM_002750

  • Clonality:

    Monoclonal

  • HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAPK8 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAPK8. Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.

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  • Amount:100ul
  • Price:255.00$

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