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UGP2 Rabbit Polyclonal Antibody (C-term)
Datasheet   

  • Catalog Number:

    E28PB2107

  • Amount:

    100ul

  • Price:

    255$

  • Altername:

    UTP--glucose-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, UGPase, UGP2, UGP1

  • Applications:

    IHC-P, WB

  • Reactivity:

    Human

  • Human Gene Id:

    NP_001001521.1;NP_006750.3

  • Swiss-Prot No.:

    Q16851

  • Specificity:

    This UGP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-497 amino acids from the C-terminal region of human UGP2.

  • Recommended Dilutions:

    WB~~1:2000;IHC-P~~1:100~500

  • Predicted Molecular Weight:

    57kDa

  • Form of Antibody:

    Liquid

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Isotype:

    Rabbit Ig

  • Background:

    UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue,UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.

  • Tissue Expression:

    Highly expressed in various brain regions. Expressed in amygdala, anterior cingulate cortex, caudate, cerebellar hemisphere, cerebellum, cortex, frontal cortex, hippocampus, hypothalamus, nucleus accumbens, putamen, spinal cord and substantia nigra (PubMed:31820119). Also widely expressed among other tissues, including liver, heart, placenta, lung, kidney, pancreas and skeletal muscle (PubMed:8354390, PubMed:8631325).

  • Cellular localization:

    Cytoplasm

  • Purification:

    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

  • All lanes : Anti-UGP2 Antibody (C-term) at 1:2000 dilution
    Lane 1: A2058 whole cell lysate
    Lane 2: HepG2 whole cell lysate
    Lane 3: Human liver lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

    Predicted band size : 57 kDa

    Blocking/Dilution buffer: 5% NFDM/TBST.

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  • Amount:100ul
  • Price:255.00$

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