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Cdx1 (18Q2) Rabbit Monoclonal Antibody
Datasheet   

  • Catalog Number:

    E28M5874

  • Amount:

    100ul

  • Cite ID#:

    EN5543322

  • Price:

    295$

  • Applications:

    WB,ICC/IF

  • Reactivity:

    Human

  • Type:

    Rabbit Monoclonal Antibody

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Altername:

    CDX1; Homeobox protein CDX 1;

  • Gene Name:

    CDX1

  • Formulation:

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Human Gene Id:

    1044

  • Swiss-Prot No.:

    P47902

  • Recommended Dilutions:

    WB 1:500~1:1000 ICC/IF 1:50~1:200

  • Predicted Molecular Weight:

    28kDa

  • Form of Antibody:

    Liquid

  • Isotype:

    Rabbit IgG

  • Tissue Expression:

    Intestinal epithelium.

  • Cellular localization:

    Nucleus.

  • Description:

    Could play a role in the terminal differentiation of the intestine.

  • Function:

    Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).

  • Western blot analysis of Cdx1 expression in Caco-2 cell lysate.

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