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Caspase-3 (7E17) Rabbit Monoclonal Antibody
Datasheet   

  • Catalog Number:

    E28M3117

  • Amount:

    100ul

  • Cite ID#:

    EN5549688

  • Price:

    295$

  • Reactivity:

    Mouse

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

  • Immunogen:

    A synthetic peptide of mouse Caspase-3

  • Applications:

    WB

  • Molecular Weight:

    32,17kDa

  • Storage/Stability:

    Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

  • Species:

    Rabbit

  • Isotype:

    IgG

  • Background:

    This gene encodes a protein that belongs to a highly conserved family of cysteinyl aspartate-specific proteases that function as essential regulators of programmed cell death through apoptosis. Members of this family contain an N-terminal pro-domain and require cleavage at specific aspartate residues to become mature. The protein encoded by this gene belongs to a subgroup of cysteinyl aspartate-specific proteases that are activated by initiator caspases and that perform the proteolytic cleavage of apoptotic target proteins. Mice defective for this gene exhibit a variety of phenotypes including reduced neuronal apoptosis resulting in hyperplasias, hearing loss, attenuated osteogenic differentiation of bone marrow stromal stem cells, and pre- and post-natal lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

  • Purification:

    Affinity Purification

  • Gene ID:

    12367

  • Altername:

    CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik

  • Recommended Dilutions:

    WB: 1:1000

  • Predicted Molecular Weight:

    32kDa

  • Form of Antibody:

    Liquid

  • Source:

    Rabbit

  • Uniprot ID:

    P70677

  • Clonality:

    Monoclonal

  • Western blot detection of Caspase-3 in C6,3T3,Hela cell lysates using Caspase-3 antibody(1:1000 diluted).

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