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(R)-Bicalutamide
Datasheet   

  • Catalog Number:

    E1KS2241
  • Amount:

    10mg
  • Kinase Inhibitor Name:

    (R)-Bicalutamide
  • Biological Activity:

    (R)-Bicalutamide is an active competitive non-steroidal androgen receptor antagonist with an IC50 of 0.17 μM for MDA 453 cells. (R)-Bicalutamide possesses virtually all activities. (R)-Bicalutamide is the leading antiandrogen. (R)-Bicalutamide is used for the treatment of prostate cancer and breast cancer. (R)-Bicalutamide prevents the activation of the androgen receptor and subsequent upregulation of androgen responsive genes by androgenic hormones. In addition, (R)-bicalutamide accelerates the degradation of the androgen receptor. [1][2][3]
  • References:

    [1] Bohl CE et al. Proc Natl Acad Sci U S A. 2005 Apr 26; 102(17):6201-6. [2] Masiello D et al. J Biol Chem. 2002 Jul 19; 277(29):26321-6. [3] Chen J et al. J Pharmacol Exp Ther. 2005 Feb; 312(2):546-53.
    The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
  • Price:

    211.2$
  • M.W.:

    430.37 Formula: C18H14F4N2O4S Solubility: Unknown Purity: >99% Storage: at -20℃ 2 years CAS No.: 113299-40-4
  • Research Area:

    Stem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction

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Catalog Number

  • Amount:10mg
  • Price:211.20$

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