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EGFR Mouse Monoclonal AntibodyPDF

  • Catalog Number:

    E12-162
  • Amount:

    100μg/100μl
  • Clone Number:

    M6
  • Background:

    The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.
  • Form of Antibody:

    Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage/Stability:

    Store at -20℃/1 year
  • Specificity/Sensitivity:

    Antibody can detects endogenous EGFR protein.
  • Reactivity:

    H
  • Applications:

    WB: 1:1,000-3,000
  • Western blot analysis of 1) A431 ,2) Hela, with E12-162 diluted at 1:2,000.
  • Price:

    225$

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Catalog Number

  • Amount:100μg/100μl
  • Price:225.00$

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