Catalog Number:
E034805Amount:
100μg/100μlPrice:
255$Species:
RabbitAntibody type:
PolyclonalPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Applications:
WBRecommended Dilutions:
Western blotting: 1:500~1:3000Reactivity:
HuSpecificity/Sensitivity:
The antibody detects endogenous levels of total MRPL50 protein.Gene Name:
MRPL50Altername:
flj20493; flj21990; mitochondrial ribosomal protein l50; mrp-l50; mrpl50Molecular Weight:
22kdImmunogen:
Synthesized peptide derived from internal of human MRPL50.Concentration:
1.0mg/mlForm of Antibody:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.Swiss-Prot No.:
Q8N5N7Gene ID:
54534;