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DHRS2 Antibody
Datasheet   

  • Catalog Number:

    E034643

  • Amount:

    100μg/100μl

  • Price:

    255$

  • Species:

    Rabbit

  • Antibody type:

    Polyclonal

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Applications:

    WB

  • Recommended Dilutions:

    Western blotting: 1:500~1:3000

  • Reactivity:

    Hu

  • Specificity/Sensitivity:

    The antibody detects endogenous levels of total DHRS2 protein.

  • Gene Name:

    DHRS2

  • Altername:

    dehydrogenase/reductase (SDR family) member 2; dehydrogenase/reductase SDR family member 2; HEP27; protein D; SDR25C1

  • Molecular Weight:

    27kd

  • Immunogen:

    Synthesized peptide derived from internal of human DHRS2.

  • Concentration:

    1.0mg/ml

  • Form of Antibody:

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

  • Background:

    Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

    Gabrielli F., Eur. J. Biochem. 232:473-477(1995).
    Pellegrini S., Biochim. Biophys. Acta 1574:215-222(2002).
    Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

  • Swiss-Prot No.:

    Q13268

  • Gene ID:

    10202;

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  • Amount:100μg/100μl
  • Price:255.00$

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