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BRCA1(Phospho-Ser1423) Antibody
Datasheet   

  • Catalog Number:

    E011242-2

  • Amount:

    100μg/100μl

  • Swiss-Prot No.:

    P38398

  • Form of Antibody:

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Storage/Stability:

    Store at -20℃/1 year

  • Immunogen:

    The antiserum was produced against synthesized phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1423 (H-G-SP-Q-P).

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

  • Specificity/Sensitivity:

    BRCA1 (phospho-Ser1423) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 1423.

  • Reactivity:

    Human

  • Applications:

    WB: 1:500~1:1000 IHC: 1:50~1:100

  • References:

    Kim ST, et al. (2002) Genes Dev; 16(5): 560-570
    Arlt MF, et al. (2004) Mol Cell Biol; 24(15): 6701-6709
    Zhang J, et al. (2004) Mol Cell Biol; 24(2): 708-718
    Greenberg RA, et al. (2006) Genes Dev; 20(1): 34-46
    Tibbetts RS, et al. (2000) Genes Dev; 14(23): 2989-3002

  • P-Peptide - +
    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using BRCA1 (phospho-Ser1423) antibody (E011242).

  • Western blot analysis of extracts from K562 cells treated with UV (20min), using BRCA1 (phospho-Ser1423) antibody (E011242, Lane 1 and 2) .

  • Price:

    225$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

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Catalog Number

  • Amount:100μg/100μl
  • Price:225.00$

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